Dobutamine

                                                           

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            Dobutamine is a synthetic catecholamine. It is a potent β1 agonist to increase myocardial contractility and cardiac output. It is also a mild alpha agonist; however, the alpha effects are counteracted by the more potent β2 properties, resulting in a mild vasodilation effect. It has a moderate to marked effect on the heart rate with increasing dose. Increases blood pressure and oxygen myocardial consumption.
 

References:

1 Gunalp B, Dokumaci B, Uyan C, Vardareli E, Isik E, Bayhan H, Ozguven M, Ozturk E. Value of dobutamine technetium-99m-sestamibi SPECT and echocardiography in the detection of coronary artery disease compared with coronary angiography. J Nucl Med. 1993 Jun;34(6):889-94.

2 Elhendy A, van Domburg RT, Bax JJ, Poldermans D, Sozzi FB, Roelandt JR. Accuracy of dobutamine technetium 99m sestamibi SPECT imaging for the diagnosisof single-vessel coronary artery disease: comparison with echocardiography. Am Heart J. 2000 Feb;139(2 Pt 1):224-30.

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