NORMAL
PARATHYROID SCINTIGRAPHY
Fifty y/o female with
elevated PTH and clinical suspicion of hyperparathyroidism underwent a
double phase and substraction 99mTc sestamibi scintigraphy. At 10 min
the thyroid gland is well visualized. At 2 h the gland washes out almost
completely. In the 99mTc perthecnetate image it is seen a homogeneous
uptake in the thyroid gland, concordant with the sestamibi 10 min scan.
In addition a right oblique view was obtained.
Tc 99m parathyroid scintigraphy is a sensitive (90%) and specific (90%)
tool for the diagnosis of adenoma, hyperplasia and carcinoma of the
parathyroid glands.
References:
1 Eslamy HK, Ziessman HA. Parathyroid scintigraphy in patients with
primary hyperparathyroidism: 99mTc sestamibi SPECT and SPECT/CT.Radiographics.
2008 Sep-Oct;28(5):1461-76.
2 Prats E, Razola P, Tardín L, Andrés A, García López F, Abós MD, Banzo
J.Parathyroid scintigraphy and radioguided surgery in primary
hyperparathyroidism.Rev Esp Med Nucl. 2007 Sep-Oct;26(5):310-28.
3 Gotthardt M, Lohmann B, Behr TM, Bauhofer A, Franzius C, Schipper ML,
Wagner M, Höffken H, Sitter H, Rothmund M, Joseph K, Nies C.Clinical
value of parathyroid scintigraphy with technetium-99m
methoxyisobutylisonitrile: discrepancies in clinical data and a
systematic metaanalysis of the literature.World J Surg. 2004 Jan;28(1):100-7.
Epub 2003 Nov 26.
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