35 y/o female with clinical suspicion of thyroid nodule. In the 99mTc pertechnectate image it is seen a homogenuos uptake in the thyroid gland in all spot views.

    Tc 99m thyroid scintigraphy is a sensitive and specific tool for localization even of small nodules and defining their function. No or low uptake in the lesion is associated in 5% to 15% with malignancy. On the other hand, increased concentration in the nodule is more common in benign  conditions (Hot Nodule).

References:

1   Sundaraiya S, Dizdarevic S, Miles K, Quin J, Williams A, Wheatley T, Zammitt C. Unusual initial manifestation of metastatic follicular carcinoma of the thyroid with thyrotoxicosis diagnosed by technetium Tc 99m pertechnetate scan: case report and review of literature.Endocr Pract. 2009 Jul-Aug;15(5):458-62.

2   Lind P, Kohlfürst S. Respective roles of thyroglobulin, radioiodine imaging, and positron emission tomography in the assessment of thyroid cancer.Semin Nucl Med. 2006 Jul;36(3):194-205.
 

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