Processing

            Use a standard backprojection technique with a Butterworth lowpass filter, the images are reconstructed and reoriented according to the anterior–posterior commissural line.

            Attenuation correction can be accomplished utilizing Chang's first order correction method.

            The interpretation is obtained visually by comparing the uptake of DAT in the caudate-putamen  versus nonspecific uptake in the occipital cortex.

References:

Chou K.L., Hurtig, HI., Stern, M.B., Colcher, A., Ravina,B., Newberg A., Mozley P.D., Siderowf, A.. Diagnostic accuracy of [99mTc]TRODAT-1 SPECT imaging in early Parkinson’s disease. Parkinsonism and Related Disorders 2004; 10: 375–379.

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