silicosis (Prepared by Dr javiera gonzalez)
Male, 47 years old with Hodgkin´s Linfocitic Lymphoma diagnosed 2009, treated
with 6 cycles of ABVD* with complete response. Control with FDG-PET/CT in 2010
showed hypermetabolic nodules in thorax (arrows). Biopsy demostrated silicosis.
In 2011 the patient had a follow up with FDG-PET/CT without significant changes
and persitent hiliar nodules with mild to moderate increased metabolism. This
patient was referred by Prof Guillermo Conte, Chief Hematology Department,
University of Chile.
(*) ABVD: Doxorrubicine (Adriamycin), Bleomicine
(Blenoxane), Vinblastine (Velban, Velsar) and Dacarbazine (DTIC-Dome).
References:
1 Abass Alavi, Naresh Gupta, Jean-Louis Alberini, Marc Hickeson, Lars-Eric Adam, Peeyush Bhargava, and Hongming Zhuang. Positron Emission Tomography Imaging in Nonmalignant Thoracic Disorders. Seminars in Nuclear Medicine, Vol XXXII, No 4 (October), 2002: pp 293-321.
2 Metin O¨ zkan, Aslı Ayan, Deniz Arik, Arzu Balkan, O¨nder O¨ngu¨ru¨, Seyfettin Gu¨mu¨s, FDG PET findings in a case with acute pulmonary silicosis. Ann Nucl Med (2009) 23:883–886.
3 Martin O’Connell and Marcus Kennedy. Progressive Massive Fibrosis Secondary to Pulmonary Silicosis Appearance on F-18 Fluorodeoxyglucose PET/CT. Clin Nucl Med 2004;29: 754–755.