Y-90 Dotatoc Therapy Patient Preparation
- In previous days, withdraw somatostatine or a any analog medication. Short acting compounds for 48 h and long acting ones for 6 weeks.
- Make sure WBC > 2400/ul or Granulocytes > 2000/ul and Platelets > 60.000/ul. Exclude DIC (disseminated intravascular coagulation).
- Determine blood creatinine concentration to estimate renal function and adjust dose if appropiate.
- Patient should fast day of therapy.
Reference:
1) Lisa Bodei, Marta Cremonesi, Chiara Grana, Paola Rocca, Mirco Bartolomei, Marco Chinol, Giovanni Paganelli. Receptor radionuclide therapy with 90Y-[DOTA]0-Tyr3-octreotide (90Y-DOTATOC) in neuroendocrine tumours. Eur J Nucl Med Mol Imaging (2004) 31:1038–1046.