Carcinoid Therapy 177Lu-DOTATATE Radiation Doses.
The table shows the radiation absorved doses of most important tissues for 177Lu-Dotatate, expressed in Rad or mGray per mCi or MBq, respectively. Note that the critical organ is the spleen. If a total dose of 100 mCi or 3700 MBq (3,7 GBq) are injected then the total body absorved dose would be of 18,5 Rad or 185 mGy, respectively.
References:
1 Wehrmann Christiane et al. Results of Individual Patient Dosimetry in Peptide Receptor Radionuclide Therapy with 177Lu DOTATATE and 177Lu DOTA-NOC. CANCER BIOTHERAPY & RADIOPHARMACEUTICALS 2007; 22: 406-416.
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